Recombinant Mouse VEGFD protein (C-6*HIS)
Species
Mouse
Purity
>90 %, SDS-PAGE
Tag
His Tag
Activity
not tested
Cat no : Eg0273
Validation Data Gallery
Product Information
| Purity | >90 %, SDS-PAGE |
| Endotoxin | <1.0 EU/μg protein, LAL method |
| Activity |
Not tested |
| Expression | HEK293-derived Mouse VEGFD protein Phe98-Ser206(Accession# P97946 ) with a His tag at the C-terminus. |
| GeneID | 14205 |
| Accession | P97946 |
| PredictedSize | 16.6 kDa |
| SDS-PAGE | |
| Formulation | Lyophilized from sterile PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| Reconstitution | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| Storage Conditions |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
Background
Vascular endothelial growth factor-D (VEGF-D) is a secreted glycoprotein that can activate VEGF receptors on the endothelium, is a mitogen for endothelial cells and promotes the growth and remodeling of blood vessels and lymphatic vessels. These vessels are located in many parts of the body and participate in a wide variety of prevalent human diseases. It is, therefore, not surprising that VEGF-D has been implicated in a multitude of disease processes from pulmonary indications to cancer.
References:
1. Stacker, S A et al. Nature medicine vol. 7,2 (2001): 186-91. 2. Achen, M G et al. Proceedings of the National Academy of Sciences of the United States of America vol. 95,2 (1998): 548-53. 3. Stacker, Steven A, and Marc G Achen. Biomolecules vol. 8,1 1.