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Recombinant Human CTHRC1 protein (rFc Tag)

Species

Human

Purity

>90 %, SDS-PAGE

Tag

rFc Tag

Activity

not tested

Cat no : Eg2824

Validation Data Gallery

  • Purity of Recombinant Human CTHRC1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Human CTHRC1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

Product Information

Purity >90 %, SDS-PAGE
Endotoxin <0.1 EU/μg protein, LAL method
Activity 
Not tested
Expression HEK293-derived Human CTHRC1 protein Ser31-Lys243 (Accession# Q96CG8-1) with a rabbit IgG Fc tag at the C-terminus.
GeneID 115908
Accession Q96CG8-1
PredictedSize 49.1 kDa
SDS-PAGE 46-55 kDa, reducing (R) conditions
Formulation Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
Reconstitution Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
Storage Conditions
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

Background

CTHRC1 is a secreted glycoprotein that plays a pivotal role in extracellular matrix (ECM) deposition and wound repair. CTHRC1 is present in normal tissues and organs, and it has vital functions in physiological processes, including participating in the regulation of metabolism, arterial remodeling, bone formation and myelination of the peripheral nervous system. It has been reported that abnormal expression of CTHRC1 is involved in the carcinogenesis of various human organs, such as the breast, colon, pancreas, lung, stomach and liver.

References:

1.Mei D. et al. (2020) Mediators Inflamm. 2020:9578701.
2.Myngbay A. et al. (2021) Int J Mol Sci. 22(5):2426. 
3.Liu YJ. et al. (2023) Oncol Lett. 25(6):266.
4.Mukhatayev Z. et al. (2024) Cells. 13(11):946.