AACS Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 13815-1-AP

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Con: 70 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse heart tissue, mouse liver tissue

Positive IF detected in:
MCF-7 cells

Recommended dilution:
WB : 1:200-1:1000
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
acetoacetyl-CoA synthetase

Calculated molecular weight:
672aa,75 kDa

Observed molecular weight:
67 kDa, 30 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AACS

Synonyms
AACS, acetoacetyl CoA synthetase, ACSF1, FLJ12389, FLJ41251, Protein sur 5 homolog, SUR 5
Background

AACS(acetoacetyl-CoA synthetase) is also named as ACSF1 and belonogs to the ATP-dependent AMP-binding enzyme family. In mammals, AACS is present in the cytosolic fractions of various tissues, especially lipogenic ones, and acetoacetate is known to be effectively incorporated into cholesterol and fatty acids. These results indicate that AACS may supply acetyl units to cytosolic compartment for cholesterol and/or fatty acid biosynthesis. It has 3 isoforms produced by alternative splicing.


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