Product Information
19764-1-PBS targets ABCA13 in WB, Indirect ELISA applications and shows reactivity with human samples.
Tested Reactivity | human |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | Peptide Predict reactive species |
Full Name | ATP-binding cassette, sub-family A (ABC1), member 13 |
Calculated Molecular Weight | 576 kDa |
Observed Molecular Weight | 576 kDa |
GenBank Accession Number | NM_152701 |
Gene Symbol | ABCA13 |
Gene ID (NCBI) | 154664 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q86UQ4 |
Storage Buffer | PBS only, pH 7.3. |
Storage Conditions | Store at -80°C. |
Background Information
ABCA13 belongs to the ABC transporter superfamily. ABCA13 is a transmembrane protein with the typical structure of ABC proteins: two transmembrane domains and two nucleotide-binding domains. ABCA13 may mediate the cholesterol and gangliosides transport from the plasma membrane to intracellular vesicles in an ATP hydrolysis-dependent manner, thus playing a role in their internalization by endocytic retrograde transport (PMID: 33478937). ABCA13 is expressed in the human trachea, testis, and bone marrow(PMID:12697998).