ABL2 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 17693-1-AP

Featured Product KD/KO validated

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Con: 38 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, Jurkat cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human liver cancer tissue, human gliomas tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)

Calculated molecular weight:
1167aa,127 kDa

Observed molecular weight:
128 kDa-140 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

Abelson related gene protein, ABL2, ABLL, ARG, Tyrosine protein kinase ABL2, Tyrosine protein kinase ARG

ABL2(Abelson tyrosine-protein kinase 2) is also named as ABLL, ARG and belongs to the protein kinase superfamily. It is a membrane-anchored nonreceptor tyrosine kinase that is a novel mediator of SEMA3F-induced RhoA inactivation and collapsing activity and it has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. ABL2 can be polyubiquitinated and the polyubiquitination of ABL2 leads to degradation. This protein has 9 isoforms produced by alternative splicing with the molecular weight from 114 kDa to 128 kDa. The antibody is specific to the others except the 60 kDa isoform of ABL2.

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