Anti-human ABL2()

ABL2 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 65041-1-Ig

Synonyms

Abelson related gene protein, ABL2, ABLL, ARG, Tyrosine protein kinase ABL2, Tyrosine protein kinase ARG



Tested Applications

Positive WB detected inHuman brain

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:2000
Sample-dependent, check data in validation data gallery

Product Information

65041-1-Ig targets ABL2 in WB, ELISA applications and shows reactivity with human samples.

Tested Reactivity human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen Recombinant Protein
Full Name v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)
Calculated molecular weight 1167aa,127 kDa
Observed molecular weight 128 kDa-140 kDa
GenBank accession number BC065912
Gene symbol ABL2
Gene ID (NCBI) 27
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at 2-8°C.

Background Information

ABL2(Abelson tyrosine-protein kinase 2) is also named as ABLL, ARG and belongs to the protein kinase superfamily. It is a membrane-anchored nonreceptor tyrosine kinase that is a novel mediator of SEMA3F-induced RhoA inactivation and collapsing activity and it has a role in cytoskeletal rearrangements by its C-terminal F-actin- and microtubule-binding sequences. ABL2 can be polyubiquitinated and the polyubiquitination of ABL2 leads to degradation. This protein has 9 isoforms produced by alternative splicing with the molecular weight from 114 kDa to 128 kDa. The antibody is specific to the others except the 60 kDa isoform of ABL2.