ACE Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 24743-1-AP

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Freight/Packing

Con: 54 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
mouse heart tissue

Positive IP detected in:
mouse heart tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1

Calculated molecular weight:
150 kDa

Observed molecular weight:
170 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ACE

Synonyms
ACE, ACE1, Angiotensin converting enzyme, CD143, DCP, DCP1, Dipeptidyl carboxypeptidase I, Kininase II, MVCD3
Background

ACE(Angiotensin-converting enzyme) is also named as DCP, DCP1 and belongs to the peptidase M2 family. It is involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. ACE also has a glycosidase activity which releases GPI-anchored proteins from the membrane by cleaving the mannose linkage in the GPI moiety. It has 4 isoforms produced by alternative splicing. The full length protein has 15 glycosylation sites and it can show a molecular weight of 170 kDa(PMID:16804085).


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