ADI1 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 15133-1-AP

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Con: 34 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human testis tissue, human testis tissue, rat colon tissue

Positive IHC detected in:
human colon cancer tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
acireductone dioxygenase 1

Calculated molecular weight:
21 kDa

Observed molecular weight:
20 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ADI1

Synonyms
Aci reductone dioxygenase, acireductone dioxygenase 1, ADI1, APL1, ARD, FLJ10913, HMFT1638, MTCBP 1, MTCBP1, SIP L, SIPL
Background

ADI1(acireductone dioxygenase 1 ) is also named as SIPL, ARD, APL1, HMFT1638, MTCBP-1, FLJ10913, MTCBP1 and belongs to the acireductone dioxygenase (ARD) family. It catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).The downregulation of ADI1 protein expression in human prostate cancer specimens argues that ADI1 potentially inhibits the growth that occurs during prostate cancer progression(PMID:17786183). It has 2 isoforms produced by alternative splicing.


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