AEBP2 Polyclonal antibody

AEBP2 Polyclonal Antibody for IP, WB,ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, ChIP,ELISA

Conjugate

Unconjugated

Cat no : 11232-2-AP

Synonyms

AE binding protein 2, AEBP2, Zinc finger protein AEBP2



Tested Applications

Positive WB detected inhuman testis tissue
Positive IP detected inmouse testis tissue

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:200-1:1000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
Sample-dependent, check data in validation data gallery

Product Information

11232-2-AP targets AEBP2 in WB, IP, ChIP,ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen AEBP2 fusion protein Ag1756
Full Name AE binding protein 2
Calculated molecular weight 33 kDa, 54 kDa
Observed molecular weight 52 kDa
GenBank accession numberBC015624
Gene symbol AEBP2
Gene ID (NCBI) 121536
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

AEBP2, also named as Zinc finger protein AEBP2 or Adipocyte enhancer-binding protein 2, is a 517 amino acid protein, which contains 3 C2H2-type zinc fingers and belongs to the AEBP2/jing C2H2-type zinc-finger family. AEBP2 as a DNA-binding transcriptional repressor may interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3. It may e playing a role in craniofacial and digital development, as well as development of the central nervous system and gastrointestinal tract.

Protocols

Product Specific Protocols
WB protocol for AEBP2 antibody 11232-2-APDownload protocol
IP protocol for AEBP2 antibody 11232-2-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseWB

Nature

Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells.

Authors - Wu Hao H
human

PLoS Genet

Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks.

Authors - Holdt Lesca M LM
mouseWB,ChIP

Nucleic Acids Res

AEBP2 as a potential targeting protein for Polycomb Repression Complex PRC2.

Authors - Kim Hana H
mouseWB

PLoS One

Aebp2 as an epigenetic regulator for neural crest cells.

Authors - Kim Hana H