AGGF1 Antibody 7 Publications

Rabbit Polyclonal| Catalog number: 11889-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

Be the first to review this product


-_-

Freight/Packing

Con: 40 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
mouse liver tissue, HEK-293 cells, HeLa cells, rat liver tissue

Positive IHC detected in:
human spleen tissue

Recommended dilution:
WB : 1:500-1:2000
IHC : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
angiogenic factor with G patch and FHA domains 1

Calculated molecular weight:
714aa,81 kDa

Observed molecular weight:
84-100 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AGGF1

Synonyms
AGGF1, Angiogenic factor VG5Q, FLJ10283, GPATC7, GPATCH7, HSU84971, HUS84971, hVG5Q, VG5Q
Background

The angiogenic factor gene, AGGF1 (or VG5Q), is identified as a candidate susceptibility gene for Klippel-Trenaunay syndrome (KTS) which is a severe congenital disorder characterized by capillary malformations, venous malformations or varicose veins, and hypertrophy of the affected tissues. AGGF1 protein can bind to endothelial cells and promote cell proliferation. AGGF1 shows strong expression in blood vessels and is secreted as vessel formation is initiated. Regulation of AGGF1 by GATA1 may play roles in endothelial cell biology and angiogenesis.


Back
to top