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  • KD/KO Validated

AGGF1 Polyclonal antibody

AGGF1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat and More (2)





Cat no : 11889-1-AP


AGGF1, Angiogenic factor VG5Q, GPATC7, GPATCH7, HSU84971, HUS84971, hVG5Q, VG5Q

Tested Applications

Positive WB detected inHUVEC cells, HeLa cells, L02 cells

Recommended dilution

Western Blot (WB)WB : 1:1000-1:8000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

11889-1-AP targets AGGF1 in WB, IP, IF, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat, macaque, Rhesus
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen AGGF1 fusion protein Ag2497
Full Name angiogenic factor with G patch and FHA domains 1
Calculated Molecular Weight 714 aa, 81 kDa
Observed Molecular Weight 84-100 kDa
GenBank Accession NumberBC029382
Gene Symbol AGGF1
Gene ID (NCBI) 55109
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

The angiogenic factor gene, AGGF1 (or VG5Q), is identified as a candidate susceptibility gene for Klippel-Trenaunay syndrome (KTS) which is a severe congenital disorder characterized by capillary malformations, venous malformations or varicose veins, and hypertrophy of the affected tissues. AGGF1 protein can bind to endothelial cells and promote cell proliferation. AGGF1 shows strong expression in blood vessels and is secreted as vessel formation is initiated. Regulation of AGGF1 by GATA1 may play roles in endothelial cell biology and angiogenesis. Catalog#11889-1-AP was validated by KO and KD methods in scientists' studies (PMID: 28153879; 27513923), and the observed MW is 84 kDa.


Product Specific Protocols
WB protocol for AGGF1 antibody 11889-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Nat Commun

A non-canonical pathway regulates ER stress signaling and blocks ER stress-induced apoptosis and heart failure.

Authors - Yufeng Yao

Mol Ther

The 3' Untranslated Region Protects the Heart from Angiotensin II-Induced Cardiac Dysfunction via AGGF1 Expression.

Authors - Lexi Ding

PLoS Biol

Angiogenic Factor AGGF1 Activates Autophagy with an Essential Role in Therapeutic Angiogenesis for Heart Disease.

Authors - Qiulun Lu
  • KO Validated

Arterioscler. Thromb. Vasc. Biol.

Angiogenic Factor With G Patch and FHA Domains 1 Is a Novel Regulator of Vascular Injury.

Authors - Bisheng Zhou
  • KD Validated

Mol Ther Nucleic Acids

circ-SHKBP1 Regulates the Angiogenesis of U87 Glioma-Exposed Endothelial Cells through miR-544a/FOXP1 and miR-379/FOXP2 Pathways.

Authors - Qianru He


Angiotensin II increases angiogenesis by NF-κB-mediated transcriptional activation of angiogenic factor AGGF1.

Authors - Wenxia Si