AIF Antibody 13 Publications

Rabbit Polyclonal| Catalog number: 17984-1-AP

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 59 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat, sheep

Positive WB detected in:
Jurkat cells, A549 cells, HeLa cells, NIH/3T3 cells, rat kidney tissue

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human kidney tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:1000-1:4000
IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB
IHC : 1:100-1:400
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
apoptosis-inducing factor, mitochondrion-associated, 1

Calculated molecular weight:
609aa,66 kDa

Observed molecular weight:
67 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AIFM1

Synonyms
AIF, AIFM1, PDCD8
Background

Apoptosis-inducing factor (AIF) is one of the mitochondrial proteins to be released into the cytosol during apoptosis, and it is discovered as the first protein that regulates caspase-independent apoptosis(PMID:20494118). AIF is encoded as a 67 kDa protein that contains a mitochondrial localization signal (MLS) in the N-terminus.It is cleaved from the 62 kDa to the 57 kDa form following ischemic injury and translocated from the mitochondria to the nucleus in a calpain-dependent manner(PMID:19332058).


Back
to top