AKIRIN1 Polyclonal antibody

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  IP experiment of U-251 using 22649-1-AP

  IP result of anti-AKIRIN1 (IP:22649-1-AP, 4ug; Detection:22649-1-AP 1:500) with U-251 cells lysate 1200 ug.

AKIRIN1 Polyclonal Antibody for IP, ELISA

Cat No. 22649-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IP, ELISA

Synonyms

akirin 1, C1orf108, RP11 781D11.2, STRF2

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Tested Applications

• Positive IP detected in: U-251 cells

Recommended dilution

• Immunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

22649-1-AP targets AKIRIN1 in IP, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: AKIRIN1 fusion protein Ag18530
• Full Name: akirin 1
• Calculated Molecular Weight: 192 aa, 22 kDa
• Observed Molecular Weight: 22 kDa
• GenBank Accession Number: BC119745
• Gene Symbol: AKIRIN1
• Gene ID (NCBI): 79647
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q9H9L7
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Akirin1 is a highly conserved ubiquitously expressed nuclear protein harboring a clear nuclear localization signal and the protein-protein interaction property. Acting as a cofactor, Akirin1 has been disclosed that regulate transcriptional activities by establishing a link between multiple transcription factors and chromatin remodeling complexes (PMID: 39188701) . Akirin1 has been shown to be involved in the induction of cardiac hypertrophy via miR-1 and serum response factor (SRF) in mice (PMID: 30746755).