ALDOB Antibody 4 Publications

Rabbit Polyclonal| Catalog number: 18065-1-AP

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Freight/Packing

Con: 62 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse kidney tissue, mouse kidney tissue, mouse liver tissue, mouse skeletal muscle tissue

Positive IP detected in:
mouse kidney tissue

Positive IHC detected in:
human liver tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:3000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
aldolase B, fructose-bisphosphate

Calculated molecular weight:
316aa,35 kDa

Observed molecular weight:
35-40 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
ALDOB

Synonyms
ALDB, ALDOB, Liver type aldolase
Background

Fructose-1,6-bisphosphate aldolase is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate.Vertebrates have 3 aldolase isozymes, aldolase A , B(ALDOB), and C. Deficiency of this enzyme ALDOB causes an accumulation of fructose-1-phosphate after fructose intake, which results in toxic symptoms like vomiting, hypoglycemia, jaundice, elevated liver enzymes and hepatomegaly(PMID:22375183).


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