AMBRA1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 13762-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 33 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse brain tissue, HepG2 cells, HT-1080 cells, human brain tissue, MCF-7 cells

Positive IHC detected in:
human liver cancer tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
autophagy/beclin-1 regulator 1

Calculated molecular weight:
1208aa,133 kDa

Observed molecular weight:
130-135 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
AMBRA1

Synonyms
AMBRA1, autophagy/beclin 1 regulator 1, FLJ20294, KIAA1736, WDR94
Background

AMBRA1 (Activating molecule in BECN1-regulated autophagy protein 1), also known as WDR94 or KIAA1736, is a 1,298 amino acid protein that contains three WD repeats. AMBRA1 regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation. This antibody works well in WB, IHC and IF application.


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