• Featured Product
  • KD/KO Validated

Angiopoietin 1 Polyclonal antibody

Angiopoietin 1 Polyclonal Antibody for IF, WB,ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 23302-1-AP


AGP1, AGPT, ANG 1, ANG1, angiopoietin 1, Angiopoietin-1, ANGPT1, KIAA0003

Tested Applications

Positive WB detected inmouse heart tissue, mouse liver tissue, HepG2 cells, A375 cells, rat heart tissue
Positive IF detected inHeLa cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
Immunofluorescence (IF)IF : 1:50-1:500
Sample-dependent, check data in validation data gallery

Product Information

The immunogen of 23302-1-AP is Angiopoietin 1 Fusion Protein expressed in E. coli.

Tested Reactivity human, mouse, rat
Cited Reactivity human, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Angiopoietin 1 fusion protein Ag18829
Full Name angiopoietin 1
Calculated molecular weight 498 aa, 58 kDa
Observed molecular weight 70 kDa
GenBank accession numberBC152411
Gene symbol ANGPT1
Gene ID (NCBI) 284
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

Angiopoietin 1 is a 70-kDa secreted glycoprotein generated from vascular mural cells, pericytes, and certain other cells. Angiopoietin 1 participates in vascular differentiation through angiogenesis, which is the process of the growth and remodelling of existing vessels. Angiopoietin 1 is also involved in the maintenance and turnover of blood vessels in mature animals. Angiopoietin 1 binds to and activates the TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation, playing an important role in the regulation of angiogenesis. Overexpression of Angiopoietin 1 has been proven to occur in malignant glioblastoma, neuroblastoma, non-small cell lung cancer, and other tumors.


Product Specific Protocols
WB protocol for Angiopoietin 1 antibody 23302-1-APDownload protocol
IF protocol for Angiopoietin 1 antibody 23302-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Biomed Pharmacother

Sinomenine mitigates collagen-induced arthritis mice by inhibiting angiogenesis.

Authors - Zhi-Tao Feng

CNS Neurosci Ther

Dl-3-N-butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats.

Authors - Pan-Ting Zhou

J Cell Mol Med

IGFBP-4 enhances VEGF-induced angiogenesis in a mouse model of myocardial infarction.

Authors - Da Wo


Silicon Oxynitrophosphide Nanoscale Coating Enhances Antioxidant Marker-Induced Angiogenesis During in vivo Cranial Bone-Defect Healing.

Authors - Felipe A do Monte

Cell Biochem Biophys

Hyperoxia-induced S1P1 signaling reduced angiogenesis by suppression of TIE-2 leading to experimental bronchopulmonary dysplasia.

Authors - Tara Sudhadevi

Neurosci Lett

Repulsive guidance molecule a suppresses angiogenesis after ischemia/reperfusion injury of middle cerebral artery occlusion in rats.

Authors - Yu Wang