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AP1M1 Polyclonal antibody
AP1M1 Polyclonal Antibody for IP, WB,ELISA
Host / Isotype
Rabbit / IgG
human, mouse, rat and More (1)
WB, IP, IF, ELISA
Cat no : 12112-1-AP
|Positive WB detected in||human brain tissue, Hacat cells|
|Positive IP detected in||SH-SY5Y cells|
|Western Blot (WB)||WB : 1:500-1:1000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB|
|Sample-dependent, check data in validation data gallery|
|KD/KO||See 4 publications below|
|WB||See 7 publications below|
|IF||See 1 publications below|
12112-1-AP targets AP1M1 in WB, IP, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, canine|
|Host / Isotype||Rabbit / IgG|
|Immunogen||AP1M1 fusion protein Ag2757|
|Full Name||adaptor-related protein complex 1, mu 1 subunit|
|Calculated molecular weight||423 aa, 49 kDa|
|Observed molecular weight||49 kDa|
|GenBank accession number||BC017469|
|Gene ID (NCBI)||8907|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
AP1M1, also named as CLTNM, Mu-adaptin 1 and Clathrin coat assembly protein AP47, belongs to the adaptor complexes medium subunit family. It is a subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
|Product Specific Protocols|
|WB protocol for AP1M1 antibody 12112-1-AP||Download protocol|
|IP protocol for AP1M1 antibody 12112-1-AP||Download protocol|
|Click here to view our Standard Protocols|
Nat Cell Biol
Plasma membrane contributes to the formation of pre-autophagosomal structures.
AP-1A controls secretory granule biogenesis and trafficking of membrane secretory granule proteins.
J Biol Chem
Adaptor Protein-1 Complex Affects the Endocytic Trafficking and Function of Peptidylglycine α-Amidating Monooxygenase, a Luminal Cuproenzyme.
Dioscin alleviates Alzheimer's disease through regulating RAGE/NOX4 mediated oxidative stress and inflammation.
Basolateral BMP signaling in polarized epithelial cells.
The interaction between HIV-1 Nef and adaptor protein-2 reduces Nef-mediated CD4(+) T cell apoptosis.