Apolipoprotein CIII Polyclonal antibody, PBS Only

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  WB analysis of human plasma using 22262-1-AP (same clone as 22262-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 22262-1-AP (APOC3 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22262-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 22262-1-AP (same clone as 22262-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22262-1-AP (APOC3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22262-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 22262-1-AP (same clone as 22262-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22262-1-AP (APOC3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22262-1-PBS in a different storage buffer formulation.

Apolipoprotein CIII Polyclonal Antibody for WB, IHC, Indirect ELISA

Cat No. 22262-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, Indirect ELISA

Synonyms

APOC3, Apo CIII, ApoC III, APOCIII, Apo-CIII

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Product Information

22262-1-PBS targets Apolipoprotein CIII in WB, IHC, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Peptide
• Full Name: apolipoprotein C-III
• Calculated Molecular Weight: 11 kDa
• Observed Molecular Weight: 11 kDa
• GenBank Accession Number: NM_000040
• Gene Symbol: Apolipoprotein CIII
• Gene ID (NCBI): 345
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P02656
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Apolipoprotein CIII (apoCIII) is the most abundant C-apolipoprotein in human and is found on very low density lipoproteins, chylomicrons, and high density lipoproteins (HDL) (PMID: 18408013). ApoCIII inhibits lipoprotein lipase as well as binding of lipoproteins to cell surface heparan sulfate proteoglycans and receptors (PMID: 26228667). ApoC-III has 3 actions that can impair plasma lipoprotein metabolism and lead to hypertriglyceridemia (PMID: 24941081).