BBS2 Polyclonal antibody
BBS2 Polyclonal Antibody for IF, IP, WB, ELISA
Host / Isotype
Rabbit / IgG
human, mouse, rat
WB, IP, IHC, IF, ELISA
Cat no : 11188-2-AP
|Positive WB detected in||mouse testis tissue|
|Positive IP detected in||mouse testis tissue|
|Positive IF detected in||hTERT-RPE1 cells|
|Western Blot (WB)||WB : 1:500-1:3000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB|
|Immunofluorescence (IF)||IF : 1:20-1:200|
|Sample-dependent, check data in validation data gallery|
|WB||See 3 publications below|
|IHC||See 2 publications below|
|IF||See 8 publications below|
11188-2-AP targets BBS2 in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||BBS2 fusion protein Ag1662|
|Full Name||Bardet-Biedl syndrome 2|
|Calculated molecular weight||80 kDa|
|Observed molecular weight||80 kDa|
|GenBank accession number||BC014140|
|Gene ID (NCBI)||583|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
BBS2 is one of seven BBS proteins that form the stable core of a protein complex (BBSome complex, 438kd) which is required for ciliogenesis but is dispensable for centriolar satellite function.
|Product Specific Protocols|
|WB protocol for BBS2 antibody 11188-2-AP||Download protocol|
|IP protocol for BBS2 antibody 11188-2-AP||Download protocol|
|Click here to view our Standard Protocols|
The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia.
Cell Stem Cell
Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes lineage progression.
J Cell Biol
Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling.
Brain Struct Funct
A novel form of ciliopathy underlies hyperphagia and obesity in Ankrd26 knockout mice.
Hum Mol Genet
Essential role of nephrocystin in photoreceptor intraflagellar transport in mouse.
Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary entry of membrane protein, Hedgehog signaling, and embryogenesis.
The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.
Deng (Verified Customer) (07-30-2019)
This antibody stained primary cilia in cultured IMCD3 cells.