BDNF Antibody 8 Publications

Rabbit Polyclonal| Catalog number: 25699-1-AP

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Freight/Packing

Con: 44 μg/150 μl

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Species specificity:
human, rat, mouse

Positive WB detected in:
fetal human brain tissue, rat brain tissue

Positive IHC detected in:
human gliomas tissue, human gliomas tissue, human skeletal muscle tissue, human testis tissue

Positive IF detected in:
PC-12 cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:50-1:500
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
brain-derived neurotrophic factor

Calculated molecular weight:
247aa,28 kDa

Observed molecular weight:
28 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BDNF

Synonyms
Abrineurin, BDNF
Background

BDNF is a member of the family of neurotrophic factors. It was first explored and purified from pig brain in 1982, and other members of the neurotrophin family were successively discovered. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimer's and Huntington disease patients. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It also plays a role in the regulation of stress response and in the biology of mood disorders.


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