BID Antibody 19 Publications

Rabbit Polyclonal| Catalog number: 10988-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 34 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HepG2 cells,HeLa cells, human brain tissue, HEK-293 cells, A431 cells, Jurkat cells, A549 cells, Tunicamycin treated HeLa cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human colon cancer tissue, human colon cancer tissue, human pancreas tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
BH3 interacting domain death agonist

Calculated molecular weight:
22 kDa

Observed molecular weight:
22 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
BID

Synonyms
BID, FP497, p11 BID, p22 BID
Background

BID, also named as p22 BID, can be cleaved into p11 BID, p13 BID and p15 BID. It is pro-apoptotic molecules. The major proteolytic product p15 BID allows the release of cytochrome c. BID-L, BID-EL and BID-ES induce ICE-like proteases and apoptosis. BID-S does not induce apoptosis. BID counters the protective effect of Bcl-2. (PMID:14583606)


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