BMP2 Monoclonal antibody
BMP2 Monoclonal Antibody for IHC, WB,ELISA
Host / Isotype
Mouse / IgG2a
human, pig and More (2)
WB, IHC, Cell treatment, ELISA
Cat no : 66383-1-Ig
|Positive WB detected in||pig bone marrow tissue, Caco-2 cells, HeLa cells|
|Positive IHC detected in||human small intestine tissue|
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
|Western Blot (WB)||WB : 1:1000-1:4000|
|Immunohistochemistry (IHC)||IHC : 1:50-1:500|
|Sample-dependent, check data in validation data gallery|
66383-1-Ig targets BMP2 in WB, IHC, Cell treatment, ELISA applications and shows reactivity with human, pig samples.
|Tested Reactivity||human, pig|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Mouse / IgG2a|
|Immunogen||BMP2 fusion protein Ag13501|
|Full Name||bone morphogenetic protein 2|
|Calculated molecular weight||396 aa, 44 kDa|
|Observed molecular weight||45 kDa|
|GenBank accession number||BC069214|
|Gene ID (NCBI)||650|
|Purification Method||Protein A purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.
|Product Specific Protocols|
|WB protocol for BMP2 antibody 66383-1-Ig||Download protocol|
|IHC protocol for BMP2 antibody 66383-1-Ig||Download protocol|
|Click here to view our Standard Protocols|
Linalool inhibits the angiogenic activity of endothelial cells by downregulating intracellular ATP levels and activating TRPM8.
Neuron-specific enolase promotes stem cell-like characteristics of small-cell lung cancer by downregulating NBL1 and activating the BMP2/Smad/ID1 pathway.
Increased Methyl-CpG-Binding Domain Protein 2 Promotes Cigarette Smoke-Induced Pulmonary Hypertension.
Saturated fatty acid promotes calcification via suppressing SIRT6 expression in vascular smooth muscle cells
J Cell Mol Med
STARD3NL inhibits the osteogenic differentiation by inactivating the Wnt/β-catenin pathway via binding to Annexin A2 in osteoporosis.
Yi-Shen-Hua-Shi Granule Alleviates Adriamycin-Induced Glomerular Fibrosis by Suppressing the BMP2/Smad Signaling Pathway.