BMPR2 Polyclonal antibody

BMPR2 Polyclonal Antibody for WB, IP, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 14376-1-AP


BMP type 2 receptor, BMP type II receptor, BMPR 2, BMPR II, BMPR2, BMPR3, BMR2, BRK 3, PPH1, T ALK

Tested Applications

Positive WB detected inmouse brain tissue
Positive IP detected inmouse brain tissue

Recommended dilution

Western Blot (WB)WB : 1:1000-1:4000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

14376-1-AP targets BMPR2 in WB, IP, IF, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen BMPR2 fusion protein Ag5752
Full Name bone morphogenetic protein receptor, type II (serine/threonine kinase)
Calculated Molecular Weight 115 kDa
Observed Molecular Weight 120 kDa
GenBank Accession NumberBC052985
Gene Symbol BMPR2
Gene ID (NCBI) 659
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

BMPs (bone morphogenetic protein) are involved in endochondral bone formation and embryogenesis. BMPR2 encodes a member of the (BMP) receptor family of transmembrane serine/threonine kinases. It is a widely expressed receptor, with high mRNA expression during development in many tissues. Dimer of BMPR2 receptors (70-80 kD) forms a complex with a dimer of type I BMPR1(50-55 kD) in signal transduction. This antibody recognizes endogenous levels of total BMPR2 protein, including 115 kD precursor, 75 kD mature form and 150 kD dimer.


Product Specific Protocols
WB protocol for BMPR2 antibody 14376-1-APDownload protocol
IP protocol for BMPR2 antibody 14376-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Front Pharmacol

Novel Pyrazolo[3,4-b] Pyridine Derivative (HLQ2g) Attenuates Hypoxic Pulmonary Hypertension via Restoring cGKI Expression and BMP Signaling Pathway

Authors - Lijun Li

BMC Genomics

Multi-omics analysis reveals regulators of the response to PDGF-BB treatment in pulmonary artery smooth muscle cells.

Authors - Jidong Chen

BMC Complement Med Ther

Huangqi decoction ameliorates kidney injury in db/db mice by regulating the BMP/Smad signaling pathway

Authors - Ying Chen

Exp Gerontol

AGEs-RAGE axis causes endothelial-to-mesenchymal transition in early calcific aortic valve disease via TGF-β1 and BMPR2 signaling.

Authors - Guorong Deng

Biochem Biophys Res Commun

SPG6 supports development of acute myeloid leukemia by regulating BMPR2-Smad-Bcl-2/Bcl-xl signaling.

Authors - Jinliang Chen

Sci Rep

Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells.

Authors - Yan Zeng