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C6 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17239-1-AP

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Con: 24 μg/150 μl

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Tested Applications

Applications:
WB, IP, IHC, ELISA
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Images See all

C6 Antibody WB human blood tissue 17239-1-AP

human blood tissue were subjected to SDS PAGE followed by western blot with 17239-1-AP( C6 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours

C6 Antibody IP human plasma tissue 17239-1-AP

IP Result of anti-C6 (IP:17239-1-AP, 4ug; Detection:17239-1-AP 1:800) with human plasma tissue lysate 4000ug.

C6 Antibody IHC human liver cancer tissue 17239-1-AP

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using 17239-1-AP( C6 Antibody) at dilution of 1:50 (under 10x lens)

C6 Antibody IHC human liver cancer tissue 17239-1-AP

Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using 17239-1-AP( C6 Antibody) at dilution of 1:50 (under 40x lens)

Species specificity:
human, mouse, rat
Positive WB detected in:
human blood tissue
Positive IP detected in:
human plasma tissue
Positive IHC detected in:
human liver cancer tissue

Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Protocols

Product-specific protocols

Standard Protocols

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
C6 fusion protein Ag11083
Full name:
complement component 6
Calculated molecular weight:
934aa,105 kDa
Observed molecular weight:
105 kDa
GenBank accession number:
BC035723
Gene ID (NCBI):
729
Gene symbol
C6
Synonyms
C6, complement component 6, Complement component C6

Background

The final consequence of complement activation is formation of the membrane attack complex (MAC), a multiprotein assembly that perforates cell membranes, forming transmembrane channels. C6 is 1 of 5 late-acting proteins of complement that participate in assembly and function of the MAC. The deduced C6 protein contains 934 amino acids, including a 21-amino acid N-terminal signal sequence and 2 N-glycosylation sites. Mutations in the C6 gene are associated with complement component-6 deficiency.


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