C6 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17239-1-AP

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Con: 24 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
human blood tissue

Positive IP detected in:
human plasma tissue

Positive IHC detected in:
human liver cancer tissue

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200

Product Information


Purification method:
Antigen affinity purification


PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
complement component 6

Calculated molecular weight:
934aa,105 kDa

Observed molecular weight:
105 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

C6, complement component 6, Complement component C6

The final consequence of complement activation is formation of the membrane attack complex (MAC), a multiprotein assembly that perforates cell membranes, forming transmembrane channels. C6 is 1 of 5 late-acting proteins of complement that participate in assembly and function of the MAC. The deduced C6 protein contains 934 amino acids, including a 21-amino acid N-terminal signal sequence and 2 N-glycosylation sites. Mutations in the C6 gene are associated with complement component-6 deficiency.

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