Carbonic Anhydrase IX/CA9 Recombinant antibody, PBS Only

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  IHC staining of mouse stomach using 84233-1-RR (same clone as 84233-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse stomach tissue slide using 84233-1-RR (CA9 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84233-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse stomach using 84233-1-RR (same clone as 84233-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse stomach tissue slide using 84233-1-RR (CA9 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84233-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84233-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84233-1-RR against Human CA9 were performed. The affinity constant is below 1 pM.

Carbonic Anhydrase IX/CA9 Uni-rAb^TM Recombinant Antibody for IHC, Indirect ELISA

Cat No. 84233-1-PBS

Clone No.241573A4

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IHC, Indirect ELISA

Synonyms

CA9, CAIX, carbonic anhydrase IX, 241573A4, CA 9

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Product Information

84233-1-PBS targets Carbonic Anhydrase IX/CA9 in IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

• Tested Reactivity: human, mouse
• Host / Isotype: Rabbit / IgG
• Class: Recombinant
• Type: Antibody
• Immunogen: Carbonic Anhydrase IX/CA9 fusion protein Ag36941
• Full Name: carbonic anhydrase IX
• Calculated Molecular Weight: 459 aa, 50 kDa
• GenBank Accession Number: BC014950
• Gene Symbol: CA9
• Gene ID (NCBI): 768
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Protein A purification
• UNIPROT ID: Q16790
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

CA9 (Carbonic anhydrase 9) may be involved in the control of cell proliferation and transformation and appears to be a novel specific biomarker for a cervical neoplasia (PMID:18703501). It is a tumor-associated antigen that has been shown to have diagnostic utility in identifying cervical dysplasia and carcinoma.The protein is presentboth on the plasma membrane and in the nucleus of cells and has the molecular. (PMID: 31819036).