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  • KD/KO Validated

CaMKII Beta Polyclonal antibody

CaMKII Beta Polyclonal Antibody for IHC, IP, WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat and More (1)





Cat no : 11533-1-AP


CaM kinase II subunit beta, CAM2, CaMK II subunit beta, CAMK2, CAMK2B, CAMKB, CaMKII beta

Tested Applications

Positive WB detected inmouse brain tissue, SH-SY5Y cells, human brain tissue, rat brain tissue
Positive IP detected inmouse brain tissue
Positive IHC detected inhuman gliomas tissue, human brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

Recommended dilution

Western Blot (WB)WB : 1:1000-1:4000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
Immunohistochemistry (IHC)IHC : 1:20-1:200
Sample-dependent, check data in validation data gallery

Product Information

11533-1-AP targets CaMKII Beta in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat, zebra finches
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen CaMKII Beta fusion protein Ag2119
Full Name calcium/calmodulin-dependent protein kinase II beta
Calculated molecular weight 503 aa, 56 kDa
Observed molecular weight 50-70 kDa
GenBank accession numberBC019070
Gene symbol CAMK2B
Gene ID (NCBI) 816
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background Information

CAMK2B(Calcium/calmodulin-dependent protein kinase type II subunit beta ), also named as CAM2, CAMK2 and CAMKB, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and CaMK subfamily. It is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. CAMK2B is a member of the NMDAR signaling complex in excitatory synapses, it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity. It plays a distinct role in the induction of anergy in T lymphocytes, by differential regulation of IL10 and IL2 gene transcription suggesting MEF2A as a molecular target which can integrate different calcium signals(PMID:22578382). This protein has 8 isoforms produced by alternative splicing with the molecular weight between 50 kDa and 73 kDa. This antibody may have cross reaction with CAMK2A/D/G due to the high homology.


Product Specific Protocols
WB protocol for CaMKII Beta antibody 11533-1-APDownload protocol
IHC protocol for CaMKII Beta antibody 11533-1-APDownload protocol
IP protocol for CaMKII Beta antibody 11533-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Sci Total Environ

Neurotoxicity and biomarkers of zinc oxide nanoparticles in main functional brain regions and dopaminergic neurons.

Authors - Huanliang Liu

Front Oncol

Anti-Tumor Role of CAMK2B in Remodeling the Stromal Microenvironment and Inhibiting Proliferation in Papillary Renal Cell Carcinoma.

Authors - Qingan Jia
  • KD Validated

Front Cell Neurosci

Pin1 Is Regulated by CaMKII Activation in Glutamate-Induced Retinal Neuronal Regulated Necrosis.

Authors - Shuchao Wang

PLoS One

Adaptive Gene Regulation in the Striatum of RGS9-Deficient Mice.

Authors - Kathy Busse
zebra finches WB

Behav Brain Res

Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X.

Authors - Lisa Y So

Aging (Albany NY)

Gastrodin ameliorates learning and memory impairment in rats with vascular dementia by promoting autophagy flux via inhibition of the Ca2+/CaMKII signal pathway.

Authors - Ting-Ting Chen