CASK Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 55277-1-AP

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Con: 41 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse kidney tissue, mouse brain tissue, mouse liver tissue

Recommended dilution:
WB : 1:500-1:1000

Product Information


Purification method:
Antigen affinity purification


PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
calcium/calmodulin-dependent serine protein kinase (MAGUK family)

Calculated molecular weight:
105 kDa

Observed molecular weight:
100-110 kDa,50-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

CAGH39, CASK, CMG, FGS4, hCASK, LIN2, MICPCH, Protein lin 2 homolog, TNRC8

CASK, also named as LIN2, belongs to the MAGUK family. It is a multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. It contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1. CASK binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. It may mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1. Defects in CASK are the cause of mental retardation X-linked CASK-related (MRXCASK) . Defects in CASK are the cause of FG syndrome type 4 (FGS4). This antibody can recognize all the isoform of CASK.

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