CD200R1 Polyclonal antibody, PBS Only

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  WB analysis using 30013-1-AP (same clone as 30013-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30013-1-AP (CD200R1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30013-1-PBS in a different storage buffer formulation.

CD200R1 Polyclonal Antibody for WB, Indirect ELISA

Cat No. 30013-1-PBS

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Synonyms

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Product Information

30013-1-PBS targets CD200R1 in WB, Indirect ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: fusion protein
• Full Name: CD200 receptor 1
• Observed Molecular Weight: 33-36 kDa
• GenBank Accession Number: BC069743
• Gene Symbol: CD200R1
• Gene ID (NCBI): 131450
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: Q8TD46
• Storage Buffer: PBS only, pH 7.3.
• Storage Conditions: Store at -80°C.

Background Information

Cell surface glycoprotein CD200 receptor 1 (CD200R1) is also named as CD200R, CRTR2, MOX2R and OX2R, and belongs to the CD200R family. CD200R1 is inhibitory receptor for the CD200/OX2 cell surface glycoprotein. CD200R1 is highly glycosylated, containing ten potential N-glycosylation sites (PMID: 15187158). CD200R1 limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. As an immune inhibitory molecule, CD200R1 binds to CD200, ultimately leading to inhibition of classical activation of macrophages and microglia (PMID: 24588829).