CD320 Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 10343-1-AP

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Con: 32 μg/150 μl

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Species specificity:
human, mouse, cat, dog

Positive WB detected in:
HEK-293 cells, HL-60 cells, human liver tissue, mouse heart tissue, Raji cells

Positive IHC detected in:
human tonsillitis tissue

Positive FC detected in:
HL-60 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Purification method:
Antigen affinity purification


PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
CD320 molecule

Calculated molecular weight:
29 kDa

Observed molecular weight:
50-55 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

8D6, 8D6 antigen, 8D6A, CD320, CD320 antigen, CD320 molecule, FDC signaling molecule 8D6, FDC SM 8D6, TCblR, Transcobalamin receptor

CD320, also known as 8D6, 8D6A or TCblR, is a single-pass type I membrane protein containing 2 LDL-receptor class A domains. Expressed abundantly on follicular dendritic cells (FDCs), CD320 has been shown to enhance proliferation of germinal center (GC) B cells. It is the receptor for cellular uptake of transcobalamin-bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC). CD320 has a calculated molecular mass of 29kD. The 58kd size by SDS-PAGE suggests extensive glycosylation of the membrane-anchored protein.

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