CD34 Antibody 7 Publications

Rabbit Polyclonal| Catalog number: 14486-1-AP

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Freight/Packing

Con: 37 μg/150 μl

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Species specificity:
human, mouse

Positive WB detected in:
HL-60 cells

Positive IHC detected in:
human hysteromyoma tissue, human endometrial cancer tissue, human small intestine tissue, human liver cancer tissue, human liver tissue, human gliomas tissue, human tonsillitis tissue

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CD34 molecule

Calculated molecular weight:
41 kDa

Observed molecular weight:
105-120 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CD34

Synonyms
CD34, CD34 molecule
Background

CD34 is a surface glycophosphoprotein expressed on developmentally early lymphohematopoietic stem and progenitor cells with a molecular weight of about 105-120 kDa. It is selectively expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nerve tissue. CD34 is a commonly used marker for identifying human hematopoietic stem/progenitor cells and mediates cell adhesion and lymphocyte homing by binding L-selectin and E-selectin ligands. CD34 is also one of the best negative selection markers for characterizing and/or isolating human MSCs from bone marrow and other sources. Along with other positive selection markers (such as CD29, CD44, CD90, CD105 and CD166), negative selection markers (such as CD34 and CD45) are used for MSC identification. This antibody 14486-1-AP is raised against 33-286 amino acids of full protein.


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