CD59 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10742-1-AP

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Freight/Packing

Con: 20 μg/150 μl

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Species specificity:
human

Positive WB detected in:
BxPC-3 cells, human brain tissue

Positive IHC detected in:
human tonsillitis tissue, human ovary tumor tissue, human placenta tissue

Positive IF detected in:
BxPC-3 cells

Positive FC detected in:
Jurkat cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:50-1:500
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
CD59 molecule, complement regulatory protein

Calculated molecular weight:
19 kDa

Observed molecular weight:
18-20 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CD59

Synonyms
16.3A5, 1F5, 1F5 antigen, CD59, CD59 glycoprotein, EJ16, EJ30, EL32, FLJ38134, FLJ92039, G344, HRF 20, HRF20, MAC inhibitory protein, MAC IP, MACIF, MEM43, MEM43 antigen, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18 20, Protectin
Background

CD59, also named as MIC11, MIN1, MIN2, MIN3, MSK21, MIRL, MACIF, HRF20 and 1F5 antigen, is a cell surface molecule glycoprotein with MW 18-25kd. It acts as a determinant of proximal–distal cell identity. CD59 acts by binding to the C8 and/or C9 complements of the assembling membrane attack complex (MAC), thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. It is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.


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