APC Anti-Human CD95 (DX2)
CD95 Monoclonal Antibody for FC
Host / Isotype
Mouse / IgG1, kappa
APC Fluorescent Dye
Cat no : APC-65071
|Positive FC detected in
|Human peripheral blood lymphocytes
|This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 10 µl per 10^6 cells in a 100 µl suspension or 10 µl per 100 µl of whole blood.
|Sample-dependent, check data in validation data gallery
APC-65071 targets CD95 in FC applications and shows reactivity with Human samples.
|Host / Isotype
|Mouse / IgG1, kappa
|Human CD95 transfected L cells
|Fas (TNF receptor superfamily, member 6)
|Calculated molecular weight
|GenBank accession number
|Gene ID (NCBI)
|APC Fluorescent Dye
|Excitation/Emission maxima wavelengths
|650 nm / 660 nm
|PBS with 0.1% sodium azide and a stabilizer.
|Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.
Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.