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  • KD/KO Validated

CDX2 Monoclonal antibody

CDX2 Monoclonal Antibody for WB, IF, ELISA

Host / Isotype

Mouse / IgG1


human, pig







Cat no : 60243-1-Ig


caudal type homeobox 2, Caudal type homeobox protein 2, CDX 3, CDX2, CDX-2, CDX3, Homeobox protein CDX 2

Tested Applications

Positive WB detected inCOLO 320 cells, HT-29 cells, SW 1990 cells, pig colon tissue
Positive IF detected inCaco-2 cells

Recommended dilution

Western Blot (WB)WB : 1:1000-1:6000
Immunofluorescence (IF)IF : 1:400-1:1600
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

The immunogen of 60243-1-Ig is CDX2 Fusion Protein expressed in E. coli.

Tested Reactivity human, pig
Cited Reactivityhuman
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Immunogen CDX2 fusion protein Ag17644
Full Name caudal type homeobox 2
Calculated Molecular Weight 313 aa, 34 kDa
Observed Molecular Weight 33-40 kDa
GenBank Accession NumberBC014461
Gene Symbol CDX2
Gene ID (NCBI) 1045
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

CDX2, also named as Homeobox protein CDX-2, is a 313 amino acid protein, which contains one homeobox DNA-binding domain and belongs to the Caudal homeobox family. CDX2 localizes in the nucleus and is involved in the transcriptional regulation of multiple genes expression in the intestinal epithelium. The relative expression of CDX1 to CDX2 protein may be important in the anterior to posterior patterning of the intestinal epithelium and in defining patterns of proliferation and differentiation along the crypt-villus axis. Both Cdx1 and Cdx2 genes must be expressed to reduce tumorigenic potential, to increase sensitivity to apoptosis, and to reduce cell migration, suggesting that the two genes control the normal phenotype by independent pathways.


Product Specific Protocols
WB protocol for CDX2 antibody 60243-1-IgDownload protocol
IF protocol for CDX2 antibody 60243-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Aging (Albany NY)

The role of CDX2 in renal tubular lesions during diabetic kidney disease.

Authors - Huiming Liu
  • KD Validated

Mediators Inflamm

Vitronectin Destroyed Intestinal Epithelial Cell Differentiation through Activation of PDE4-Mediated Ferroptosis in Inflammatory Bowel Disease

Authors - Wenxu Pan

J Reprod Immunol

Poly(I:C) exposure during in vitro fertilization disrupts first cleavage of mouse embryos and subsequent blastocyst development.

Authors - Zhicheng Wang

Chem Biol Interact

6-Formylindolo(3,2-b)carbazole induced aryl hydrocarbon receptor activation prevents intestinal barrier dysfunction through regulation of claudin-2 expression.

Authors - Yuanhang Ma
  • KD Validated

World J Gastrointest Oncol

Xiaojianzhong decoction prevents gastric precancerous lesions in rats by inhibiting autophagy and glycolysis in gastric mucosal cells

Authors - Jia-Xiang Zhang

Mol Reprod Dev

Ratio of the zygote cytoplasm to the paternal genome affects the reprogramming and developmental efficiency of androgenetic embryos.

Authors - Chen Liao