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Anti-Human CEACAM6/CD66c Rabbit Recombinant Antibody, PBS Only (98329-3-PBS)

Anti-Human CEACAM6/CD66c Rabbit Recombinant Antibody, PBS Only

Name: Anti-Human CEACAM6/CD66c Rabbit Recombinant Antibody, PBS Only, 1mg
Brand: Proteintech
SKU: 98329-3-PBS-1MG

CEACAM6/CD66c Uni-rAb^® Recombinant Antibody for FC

Cat No. 98329-3-PBS

Clone No. 241997G1

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Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Synonyms

CEACAM6, 241997G1, Carcinoembryonic antigen-related cell adhesion molecule 6, CD66c, CEAL

Formulation: PBS Only

PBS, Azide

PBS Only

Conjugate: Unconjugated

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Filter: AllFC

FC experiment of human peripheral blood leukocytes using 98329-3-RR (same clone as 98329-3-PBS)
1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CEACAM6/CD66c Rabbit RecAb (98329-3-RR, Clone: 241997G1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98329-3-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CEACAM6/CD66c Rabbit RecAb (98329-3-RR, Clone: 241997G1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98329-3-PBS in a different storage buffer formulation.
FC experiment of human peripheral blood leukocytes using 98329-3-RR (same clone as 98329-3-PBS)
1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CEACAM6/CD66c Rabbit RecAb (98329-3-RR, Clone:241997G1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98329-3-PBS in a different storage buffer formulation.
This validation data has been generated in-house and reviewed by Proteintech scientists. Find out more on our antibody validation policy
×
1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CEACAM6/CD66c Rabbit RecAb (98329-3-RR, Clone:241997G1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98329-3-PBS in a different storage buffer formulation.

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Overview

Tested Applications
Product Information

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MSDS SDS

Product Information

98329-3-PBS targets CEACAM6/CD66c in FC applications and shows reactivity with human samples.

Tested Reactivity	human
Host / Isotype	Rabbit / IgG
Class	Recombinant
Type	Antibody
Immunogen	CatNo: Eg2450 Product name: recombinant human CEACAM6 protein Source: mammalian cells-derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 35-320 aa of BC005008 Sequence: KLTIESTPFNVAEGKEVLLLAHNLPQNRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDVPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQAHNSATGLNRTTVTMITVSG Predict reactive species
Full Name	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
Calculated Molecular Weight	37 kDa
GenBank Accession Number	BC005008
Gene Symbol	CEACAM6
Gene ID (NCBI)	4680
RRID	AB_3745980
Conjugate	Unconjugated
Form	Liquid
Purification Method	Protein A purification
UNIPROT ID	P40199
Storage Buffer	PBS only, pH 7.3.
Storage Conditions	Store at -80°C.

Background Information

Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to the immunoglobulin superfamily of cell adhesion molecules. CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in controlling cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM6, also known as CD66c, is a glycosylphosphatidylinositol (GPI)-linked cell surface protein that belongs to the CEACAM family of the immunoglobulin superfamily (PMID: 23903773). It is normally expressed on the surface of myeloid and epithelial surfaces and upregulated preferentially at the apical/luminal membranes of many tumors (PMID: 27595061; 35082925). CEACAM6 plays an important role in cell adhesion, proliferation, tumorigenesis, metastasis, and immunity (PMID: 31797958).