CEACAM8 Polyclonal antibody

• 

  WB analysis using 30875-1-AP

  human saliva tissue were subjected to SDS PAGE followed by western blot with 30875-1-AP (CEACAM8 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours.

CEACAM8 Polyclonal Antibody for WB, ELISA

Cat No. 30875-1-AP

Publications(1)

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF, ELISA

Synonyms

CD66b, CD66b antigen, CD 67, CD 66b, Carcinoembryonic antigen-related cell adhesion molecule 8

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Tested Applications

• Positive WB detected in: human saliva

Recommended dilution

• Western Blot (WB): WB : 1:2000-1:16000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Published Applications

• IHC: See 1 publications below
• IF: See 1 publications below

Product Information

30875-1-AP targets CEACAM8 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.

• Tested Reactivity: human
• Cited Reactivity: human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: Recombinant protein
• Full Name: carcinoembryonic antigen-related cell adhesion molecule 8
• Calculated Molecular Weight: 38 kDa
• Observed Molecular Weight: 95-100kDa
• GenBank Accession Number: BC026263
• Gene Symbol: CEACAM8
• Gene ID (NCBI): 1088
• RRID: AB_3669772
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity purification
• UNIPROT ID: P31997
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Carcinoembryonic antigen-related cell adhesion molecule 8 (CEACAM8), also known as CD66b, CGM6 or NCA-95, is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAM8 is a glycosylphosphatidylinositol (GPI)-linked glycoprotein expressed on granulocytes (PMID: 8104998; 18056392). It is involved in regulating adhesion and activation of eosinophils (PMID: 18056392).

Publications

Species	Application	Title
human	IHC,IF	Transl Res; Single-cell RNA sequencing reveals the MIF/ACKR3 receptor-ligand interaction between neutrophils and nucleus pulposus cells in intervertebral disc degeneration; Authors - Tao-Lan Zhang