COQ2 Polyclonal antibody

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  WB analysis using 30909-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 30909-1-AP (COQ2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

COQ2 Polyclonal Antibody for WB, ELISA

Cat No. 30909-1-AP

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

WB, ELISA

Synonyms

CL640, COQ2, COQ2 homolog, FLJ26072, hCOQ2, PHB:polyprenyltransferase

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Tested Applications

• Positive WB detected in: HEK-293 cells, U-87 MG cells

Recommended dilution

• Western Blot (WB): WB : 1:1000-1:4000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, Check data in validation data gallery.

Product Information

30909-1-AP targets COQ2 in WB, ELISA applications and shows reactivity with Human samples.

• Tested Reactivity: Human
• Host / Isotype: Rabbit / IgG
• Class: Polyclonal
• Type: Antibody
• Immunogen: COQ2 fusion protein Ag29155
• Full Name: coenzyme Q2 homolog, prenyltransferase (yeast)
• Calculated Molecular Weight: 371 aa, 40 kDa
• Observed Molecular Weight: 35 kDa，40 kDa，45 kDa
• GenBank Accession Number: BC008804
• Gene Symbol: COQ2
• Gene ID (NCBI): 27235
• RRID: AB_3669780
• Conjugate: Unconjugated
• Form: Liquid
• Purification Method: Antigen affinity Purification
• UNIPROT ID: Q96H96
• Storage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
• Storage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20^oC storage. 20ul sizes contain 0.1% BSA.

Background Information

COQ2 (coenzyme Q2, polyprenyltransferase), also known as CL640. It is expected to be located in mitochondrion inner membrane. And the protein is highly expressed in skeletal muscle, adrenal glands and the heart. COQ2 is a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. The protein has three isforms, the calculated molecular weight are 35, 40, 45 kDa.