CPS1 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 18703-1-AP

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Con: 40 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
HepG2 cells, mouse liver tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:2000
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
carbamoyl-phosphate synthetase 1, mitochondrial

Calculated molecular weight:
165 kDa

Observed molecular weight:
116 kDa,165 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CPS1

Synonyms
CPS1, CPSase I
Background

CPS1 is an enzyme that catalyzes the first committed step of the hepatic urea cycle, which is important in the removal of excess urea from cells. Expressed primarily in the liver and small intestine, CPS1 can be used as a marker for mitochondria in these tissues. In addition, CPS1 expression appears to be lost in adenocarcinomas of the small intestine. The antibody can recognize two isoforms of this gene around 165 kDa and 116 kDa.


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