CSNK2A1 Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 10992-1-AP

Featured Product KD/KO validated

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 93 μg/150 μl

Choose size:

Please visit your regions distributor:


Species specificity:
human, mouse, rat

Positive WB detected in:
HeLa cells, HEK-293 cells, HeLa cells, Jurkat cells, NIH/3T3 cells

Positive IP detected in:
HeLa cells

Positive IHC detected in:
human gliomas tissue, human colon cancer tissue, human gliomas tissue

Positive IF detected in:
HeLa cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:2000 for WB
IHC : 1:20-1:200
IF : 1:10-1:100

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
casein kinase 2, alpha 1 polypeptide

Calculated molecular weight:
45 kDa

Observed molecular weight:
45 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CSNK2A1

Synonyms
Casein kinase II subunit alpha, CK II alpha, CK2a, CK2A1, CK2α, CKII, CSNK2A1
Background

CSNK2A1(Casein kinase II subunit alpha) is also named as CK2A1 and belongs to the CK2 subfamily. The CSNK2A1 gene contains 8 exons whose sequences comprise bases 102 to 824 of the coding region of the human casein kinase II alpha subunit. Casein kinase II is a ubiquitous protein-serine/threonine kinase in eukaryotic cells that catalyzes the phosphorylation of many protein substrates and has been regarded as a second-messenger-independent protein kinase. this enzyme is composed of an α subunit (37 to 44kDa) and aβsubunit (24 to 28 kDa) and exists as an α2β2 tetramer.(PMID:1448100). Casein kinase 2 has been found to be inccreased at protein level and up-regulated at the level of enzyme activity in the majority of cancers. However, elevated levels of casein kinase 2 are present in certain normal organs such as brain and testes.


Back
to top