CTHRC1 Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 16534-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 31 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
A375 cells, A375 cells, HEK-293 cells, Jurkat cells, mouse brain tissue, mouse lung tissue, rat lung tissue

Positive IP detected in:
A375 cells

Positive IHC detected in:
human breast cancer tissue

Positive IF detected in:
A375 cells

Recommended dilution:
WB : 1:500-1:2000
IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
collagen triple helix repeat containing 1

Calculated molecular weight:
243aa,26 kDa

Observed molecular weight:
30 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CTHRC1

Synonyms
CTHRC1, Protein NMTC1
Background

Collagen triple helix repeat-containing protein 1 (CTHRC1), also known protein NMTC1, is a glycosylated secreted protein. CTHRC1 was identified as a novel molecular in injured and diseased arteries where it may contribute to vascular remodeling by limiting collagen matrix deposition and promoting cell migration (PMID: 15618538). It has been reported that CTHRC1 is a positive regulator of osteoblastic bone formation (PMID: 18779865). Besides, studies reveal that CTHRC1 expression is implicated in various malignancies, including hepatocellular carcinoma, gastric carcinoma, colon cancer, and lung cancer (PMID: 23922981; 24504172; 24746208; 25139095).


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