CXCR3 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 26756-1-AP

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Freight/Packing

Con: 60 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HepG2 cells, Jurkat cells

Positive IHC detected in:
human liver tissue, human kidney tissue, human liver tissue

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:50-1:500

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
chemokine (C-X-C motif) receptor 3

Calculated molecular weight:
368aa,41 kDa

Observed molecular weight:
70 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CXCR3

Synonyms
CD183, CKR L2, CMKAR3, CXC R3, CXCR 3, CXCR3, CXCR3A, CXCR3B, G protein coupled receptor 9, GPR9, IP 10 receptor, IP10 R, Mig R, MigR
Background

CXCR3 (C-X-C chemokine receptor type 3) is a G-protein-coupled seven-transmembrane domain chemokine receptor that is expressed on the surface of a number of cell types, including activated CD4+and CD8+ T cells, NK and NK-T cells, plasmacytoid dendritic cells, and some B cells. CXCR3 is activated by three related chemokines (CXCL9, CXCL10, and CXCL11) and plays an important role in effector T-cell and NK cell trafficking. CXCR3 has three isoforms termed as CXCR3-A, CXCR3-B and CXCR3-alt with the calculated molecular mass of 41kDa, 46kDa and 29kDa respectively. The apparent molecular mass of CXCR3 detected by some scientists is 70kDa, but 45kDa by some others. (PMID: 16847335, 15150261, 22885102, 19151743)


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