CYB5R3 Antibody 0 Publications

Mouse Monoclonal| Catalog number: 66022-1-Ig |CloneNo.: 9C4D10

Featured Product KD/KO validated

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Freight/Packing

Con: 134 μg/150 μl

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Species specificity:
human

Positive WB detected in:
HeLa cells, human heart tissue, human plasma tissue, HepG2 cells, L02 cells

Positive IHC detected in:
human liver tissue, human liver tissue, human placenta tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:5000-1:50000
IHC : 1:20-1:200
IF : 1:50-1:500

Product Information


Source:
Mouse

Purification method:
Protein A purification

Isotype:
IgG2b

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cytochrome b5 reductase 3

Calculated molecular weight:
33 kDa

Observed molecular weight:
33 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CYB5R3

Synonyms
B5R, CYB5R3, Cytochrome b5 reductase, cytochrome b5 reductase 3, DIA1, Diaphorase 1, NADH cytochrome b5 reductase 3
Background

CYB5R3, also named as DIA1 and B5R, belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. It plays an essential role in the mitochondrial metabolism by its contribution to cellular redox homeostasis. Overstimulation of CYB5R3 associated with lipid rafts can account for the overshot of plasma membrane-focalized superoxide anion production that triggers the entry of CGN in the irreversible phase of apoptosis.


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