Cytoglobin Antibody 1 Publications

Rabbit Polyclonal| Catalog number: 13317-1-AP

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Freight/Packing

Con: 62 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
mouse heart tissue, human heart tissue, human uterus tissue, mouse brain tissue, mouse kidney tissue, mouse lung tissue, mouse small intestine tissue, mouse spleen tissue, mouse stomach tissue, PC-3 cells, rat kidney tissue, Transfected HEK-293 cells

Positive IHC detected in:
human liver cancer tissue, human heart tissue, human liver tissue, human liver cancer tissue, human prostate cancer tissue, human stomach tissue

Recommended dilution:
WB : 1:500-1:3000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Full name:
cytoglobin

Calculated molecular weight:
190aa,21 kDa

Observed molecular weight:
21-29 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
CYGB

Synonyms
CYGB, cytoglobin, HGB, Histoglobin, STAP
Background

Cytoglobin, also named as Histoglobin, HGb, STAP and CYGB, belongs to the globin family. Cytoglobin may have a protective function during conditions of oxidative stress. It may be involved in intracellular oxygen storage or transfer. It serves as a defensive mechanism against oxidative stress both in vitro and in vivo.(PMID:21224051) Cytoglobin is a ubiquitously expressed hexacoordinate hemoglobin that may facilitate diffusion of oxygen through tissues. The protein, with calculated MW of 21 kd, runs as a 29kd one in canine retina, kidney, liver, lung, and heart. It may be caused by posttranslational modification of the protein. Various immuno-staining patterns were reported including nuclear, cytoplasm and extracellular location.


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