Drebrin Polyclonal antibody
Drebrin Polyclonal Antibody for IF, IP, WB,ELISA
Host / Isotype
Rabbit / IgG
human, mouse, rat
WB, IP, IHC, IF, ELISA
Cat no : 10260-1-AP
|Positive WB detected in||HeLa cells, K-562 cells|
|Positive IP detected in||K-562 cells|
|Positive IF detected in||HeLa cells, HepG2 cells|
|Western Blot (WB)||WB : 1:500-1:3000|
|Immunoprecipitation (IP)||IP : 0.5-4.0 ug for IP and 1:1000-1:4000 for WB|
|Immunofluorescence (IF)||IF : 1:20-1:200|
|Sample-dependent, check data in validation data gallery|
|WB||See 11 publications below|
|IHC||See 3 publications below|
|IF||See 3 publications below|
|IP||See 1 publications below|
10260-1-AP targets Drebrin in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
|Tested Reactivity||human, mouse, rat|
|Cited Reactivity||human, mouse, rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Drebrin fusion protein Ag0371|
|Full Name||drebrin 1|
|Calculated molecular weight||71 kDa|
|Observed molecular weight||100-130 kDa|
|GenBank accession number||BC000283|
|Gene ID (NCBI)||1627|
|Purification Method||Antigen affinity purification|
|Storage Buffer||PBS with 0.02% sodium azide and 50% glycerol pH 7.3.|
|Storage Conditions||Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.|
Drebrin (DBN1) is an actin binding and stabilizing protein with roles in endocytosis, formation of dendrite spines in neurons and coordinating cell-cell synapses in immune cells. Preferentially expressed in the brain, it is highly localized in dendritic spines and regulates spine shapes. It has two isoforms that are splice variants, with drebrin A being expressed in neural cells, and drebrin E is present in several other cell types. Recently it has been reported that circulating DBN1 levels correlated with retinal nerve fiber layer defect and may reflect the severity of retinal ganglion cells injury in glaucoma patients.
|Product Specific Protocols|
|WB protocol for Drebrin antibody 10260-1-AP||Download protocol|
|IF protocol for Drebrin antibody 10260-1-AP||Download protocol|
|IP protocol for Drebrin antibody 10260-1-AP||Download protocol|
|Click here to view our Standard Protocols|
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