Desmocollin 2 Polyclonal antibody

Desmocollin 2 Polyclonal Antibody for IF, IHC, WB, ELISA

Host / Isotype

Rabbit / IgG


human, mouse





Cat no : 13876-1-AP


ARVD11, Cadherin family member 2, CDHF2, desmocollin 2, Desmocollin 3, Desmosomal glycoprotein II, Desmosomal glycoprotein III, DG2, DGII/III, DSC2, DSC3

Tested Applications

Positive WB detected inJurkat cells, HeLa cells, HepG2 cells
Positive IHC detected inhuman oesophagus tissue, human skin cancer tissue, mouse heart tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inmouse heart tissue

Recommended dilution

Western Blot (WB)WB : 1:500-1:2000
Immunohistochemistry (IHC)IHC : 1:500-1:2000
Immunofluorescence (IF)IF : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Product Information

13876-1-AP targets Desmocollin 2 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Desmocollin 2 fusion protein Ag4956
Full Name desmocollin 2
Calculated molecular weight 100 kDa
Observed molecular weight 110-120 kDa
GenBank accession numberBC063291
Gene symbol DSC2
Gene ID (NCBI) 1824
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

Desmocollin 2 (DSC2) is a member of the desmocollin subfamily of the cadherin superfamily. The desmocollins (DSC1-3), along with the desmogleins (DSG1-4), are found primarily in epithelia and cardiac muscle where they constitute the adhesive proteins of the intercellular desmosome junctions and are required for cell adhesion and desmosome formation. Mutations in DSC2 gene are associated with arrhythmogenic right ventricular dysplasia-11.


Product Specific Protocols
WB protocol for Desmocollin 2 antibody 13876-1-APDownload protocol
IHC protocol for Desmocollin 2 antibody 13876-1-APDownload protocol
IF protocol for Desmocollin 2 antibody 13876-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Dev Cell

Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model.

Authors - Sally Dabelsteen

Sci Total Environ

Environmental cadmium impairs blood-testis barrier via activating HRI-responsive mitochondrial stress in mice.

Authors - Guo-Xiang Zhou

Br J Cancer

Mapping of truncated O-glycans in cancers of epithelial and non-epithelial origin.

Authors - Troels Boldt Rømer

Bioconjug Chem

Transforms of Cell Surface Glycoproteins Charge Influences Tumor Cell Metastasis via Atypically Inhibiting Epithelial-Mesenchymal Transition Including Matrix Metalloproteinases and Cell Junctions

Authors - Mingzhe Wang

Mol Ther Oncolytics

Exosomal miR-205-5p enhances angiogenesis and nasopharyngeal carcinoma metastasis by targeting desmocollin-2.

Authors - Wenjuan Yang


The reviews below have been submitted by verified Proteintech customers who received an incentive forproviding their feedback.


Jane (Verified Customer) (02-03-2022)

One specific band was found around 120kDa, however, the signal is weak so need to use lower dilution

  • Applications: Western Blot
  • Primary Antibody Dilution: 1:200
  • Cell Tissue Type: Heart tissue