PERK Antibody 3 Publications

Rabbit Polyclonal| Catalog number: 24390-1-AP

  • Print page
  • Download PDF

Be the first to review this product



Con: 50 μg/150 μl

Choose size:

Please visit your regions distributor:

Species specificity:

Positive WB detected in:
HepG2 cells

Positive IHC detected in:
human pancreas tissue, human pancreas tissue, human placenta tissue

Positive IF detected in:
HepG2 cells

Recommended dilution:
WB : 1:200-1:1000
IHC : 1:20-1:200
IF : 1:20-1:200

Product Information


Purification method:
Antigen affinity purification


PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Full name:
eukaryotic translation initiation factor 2-alpha kinase 3

Calculated molecular weight:
1116aa,125 kDa

Observed molecular weight:
125 kDa, 140 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol

DKFZp781H1925, EIF2AK3, HRI, HsPEK, Pancreatic eIF2 alpha kinase, PEK, PERK, WRS

PERK is also named as PEK, EIF2AK3 (Eukaryotic translation initiation factor 2-alpha kinase 3) and belongs to the GCN2 subfamily. It acts potentially as a metabolic sensor in the insulin-secreting beta-cells to modulate the trafficking and quality control of proinsulin in the ER relative to the physiological demands for circulating insulin(PMID:20530744).PERK and EIF2AK4 also have a functional role on regulating translation under non-stressed conditions, apart from their long established roles as stress kinases(PMID: 21638082). The full length protein has a signal peptide and a glycosylation site.

to top