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EIF3H Antibody 2 Publications

Rabbit Polyclonal| Catalog number: 11310-1-AP

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Tested Applications

Applications:
WB, ELISA
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EIF3H Antibody WB HeLa cells 11310-1-AP

Various lysates were subjected to SDS PAGE followed by western blot with 11310-1-AP (EIF3H antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours

Species specificity:
human, mouse, rat
Positive WB detected in:
HeLa cells
Recommended dilution:
WB : 1:500-1:3000
Sample-dependent, check data in Validation tab

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
EIF3H fusion protein Ag1850
Full name:
eukaryotic translation initiation factor 3, subunit H
Calculated molecular weight:
40 kDa
Observed molecular weight:
40 kDa
GenBank accession number:
BC000386
Gene ID (NCBI):
8667
Gene symbol
EIF3H
Synonyms
eIF 3 gamma, eIF3 gamma, eIF3 p40, eIF3 p40 subunit, EIF3H, EIF3S3

Background

Eukaryotic translation initiation factor eIF3, that plays a central role in translation initiation, consists of five core subunits that are present in both the budding yeast and higher eukaryotes. The EIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex. The complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. It is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. EIF3H is a component of the EIF3 complex. [PMID:19204574,20503360]


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