Back

ELA2 Antibody 0 Publications

Rabbit Polyclonal| Catalog number: 17943-1-AP

  • Print page
  • Download PDF

-_-

Freight/Packing

Con: 20 μg/150 μl

Choose size:

Please visit your regions distributor:

Request quote for
bulk/custom formulations

Special offer: Add control/tag antibody for $99
Load more
Tested Applications
Applications:
ELISA, IF, IP
Application not tested? Please see our Guarantee


Images See all

ELA2 Antibody IF HEK-293 cells 17943-1-AP

Immunofluorescent analysis of ( -20℃ Ethanol) fixed HEK-293 cells using 17943-1-AP (ELA2 antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

ELA2 Antibody IP HEK-293 cells 17943-1-AP

IP Result of anti-ELA2 (IP:17943-1-AP, 4ug; Detection:17943-1-AP 1:300) with HEK-293 cells lysate 2640ug.

Species specificity:
human, mouse, rat
Positive IP detected in:
HEK-293 cells
Positive IF detected in:
HEK-293 cells
Recommended dilution:
IP : 0.5-4.0 ug for IP and 1:200-1:1000 for WB
IF : 1:50-1:500

Product Information

Source:
Rabbit
Purification method:
Antigen affinity purification
Isotype:
IgG
Storage:
PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information

Immunogen:
ELA2 fusion protein Ag12372
Full name:
elastase 2, neutrophil
Calculated molecular weight:
267aa,29 kDa
Observed molecular weight:
kDa
GenBank accession number:
BC074816
Gene ID (NCBI):
1991
Gene symbol
ELA2
Synonyms
Bone marrow serine protease, ELA2, ELANE, Elastase 2, elastase 2, neutrophil, GE, HLE, HNE, Human leukocyte elastase, Medullasin, NE, Neutrophil elastase, PMN E, PMN elastase
Background

ELA2(Neutrophil elastase) is also named as ELAL, NE, HLE, HNE, PMN-E, SERP1, GE, ELANE and belongs to the peptidase S1 family. It is a 33-kDa enzyme with several isoforms that differ in their extent of glycosylation(PMID:12223222). Human neutrophil elastase (HNE) is a serine protease with potent proteolytic activity (3), which is reported to cause mucin secretion (degranulation)(PMID:12169572). It may contribute to the directed migration of leukocytes into flamed postcapillary venules in addition to contributing to the process of tissue emigration(PMID:9683424). The full length protein has a signal peptide,propeptide and three glycosylation sites.


Back
to top