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  • KD/KO Validated

ETV4 Polyclonal antibody

ETV4 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat and More (1)

Applications

WB, IHC, IF, ELISA

Conjugate

Unconjugated

Cat no : 10684-1-AP

Synonyms

E1A F, E1AF, ETS translocation variant 4, ets variant 4, ETV4, PEA3, PEAS3, Protein PEA3



Tested Applications

Positive WB detected inmouse heart tissue, BxPC-3 cells

Recommended dilution

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

10684-1-AP targets ETV4 in WB, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, chicken
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen ETV4 fusion protein Ag0984
Full Name ets variant 4
Calculated Molecular Weight 54 kDa
Observed Molecular Weight 61 kDa
GenBank Accession NumberBC007242
Gene Symbol ETV4
Gene ID (NCBI) 2118
RRIDAB_2100984
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

ETS translocation variant 4 (ETV4), also named as E1A-F or PEA3, is 484 amino acid protein, which contains one ETS DNA-binding domain and belongs to the ETS family. The calculated molecular weight of ETV4 protein is 54 kDa, but the phosphorylated ETV4 is a 54-61 kDa protein. ETV4 as a transcription activator localizes in the nucleus and binds to the enhancer of the adenovirus E1A gene.

Protocols

Product Specific Protocols
WB protocol for ETV4 antibody 10684-1-APDownload protocol
IF protocol for ETV4 antibody 10684-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
humanWB

Cell

Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription.

Authors - Jaehong Suh
mouseWB

Dev Cell

ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization.

Authors - Lee Yoontae Y
  • KD Validated
mouseWB

Nat Commun

Capicua deficiency induces autoimmunity and promotes follicular helper T cell differentiation via derepression of ETV5.

Authors - Sungjun Park
humanWB

Cancer Res

Targeting pan-ETS factors inhibits melanoma progression.

Authors - Lee Huang
human,mouseWB

Proc Natl Acad Sci U S A

Erk1/2 inactivation promotes a rapid redistribution of COP1 and degradation of COP1 substrates.

Authors - Weiming Ouyang
humanWB

Oncogene

HDAC6-G3BP2 promotes lysosomal-TSC2 and suppresses mTORC1 under ETV4 targeting-induced low-lactate stress in non-small cell lung cancer

Authors - Bei Liu
  • KD Validated