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  • KD/KO Validated

EXOC5 Polyclonal antibody

EXOC5 Polyclonal Antibody for IF, IHC, IP, WB,ELISA

Host / Isotype

Rabbit / IgG


human, mouse, rat





Cat no : 17593-1-AP


EXOC5, exocyst complex component 5, HSEC10, PRO1912, SEC10, SEC10L1, SEC10P

Tested Applications

Positive WB detected inmouse brain tissue, human adrenal gland tissue
Positive IP detected inmouse brain tissue
Positive IHC detected inhuman testis tissue, human brain tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF detected inHepG2 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:3000
Immunoprecipitation (IP)IP : 0.5-4.0 ug for IP and 1:500-1:1000 for WB
Immunohistochemistry (IHC)IHC : 1:20-1:200
Immunofluorescence (IF)IF : 1:10-1:100
Sample-dependent, check data in validation data gallery

Product Information

17593-1-AP targets EXOC5 in WB, IP, IHC, IF, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Reactivity human, mouse, rat
Cited Reactivityhuman, mouse, rat
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen EXOC5 fusion protein Ag11524
Full Name exocyst complex component 5
Calculated molecular weight 708 aa, 82 kDa
Observed molecular weight 77 kDa
GenBank accession numberBC041126
Gene symbol EXOC5
Gene ID (NCBI) 10640
Conjugate Unconjugated
Form Liquid
Purification Method Antigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

EXOC5 (SEC10), a component of the exocyst complex, is a 77-kDa protein with a broad tissue distribution (PubMed: 9119050). The exocyst complex, composed of eight evolutionarily conserved subunits (SEC3, SEC5, SEC6, SEC8, SEC10, SEC15, EXO70, and EXO84), is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. The complex is also essential for the biogenesis of epithelial cell surface polarity.


Product Specific Protocols
WB protocol for EXOC5 antibody 17593-1-APDownload protocol
IHC protocol for EXOC5 antibody 17593-1-APDownload protocol
IF protocol for EXOC5 antibody 17593-1-APDownload protocol
IP protocol for EXOC5 antibody 17593-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols




RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly.

Authors - Bodemann Brian O BO
  • KD Validated


Functional hierarchy among different Rab27 effectors involved in secretory granule exocytosis

Authors - Kunli Zhao

Sci Rep

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

Authors - Isabel Saez

Mol Cancer Res

EXOC4 Promotes Diffuse-Type Gastric Cancer Metastasis via Activating FAK Signal.

Authors - Haojie Li
  • KD Validated


The Exocyst Is Required for CD36 Fatty Acid Translocase Trafficking and Free Fatty Acid Uptake in Skeletal Muscle Cells

Authors - Nicole K. Nakamura

J Biol Chem

Disrupted glucose homeostasis and skeletal muscle-specific glucose uptake in an exocyst knockout mouse model.

Authors - Brent A Fujimoto
  • KO Validated