FOXO4 Polyclonal antibody

FOXO4 Polyclonal Antibody for WB, IF, ELISA

Host / Isotype

Rabbit / IgG


human, mouse





Cat no : 19121-1-AP


AFX, AFX1, forkhead box O4, Forkhead box protein O4, FOXO4, MLLT7

Tested Applications

Positive WB detected inhuman heart tissue, mouse heart tissue
Positive IF detected inHepG2 cells

Recommended dilution

Western Blot (WB)WB : 1:500-1:1000
Immunofluorescence (IF)IF : 1:10-1:100
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

Product Information

19121-1-AP targets FOXO4 in WB, IF, ELISA applications and shows reactivity with human, mouse samples.

Tested Reactivity human, mouse
Cited Reactivityhuman, mouse
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Immunogen Peptide
Full Name forkhead box O4
Calculated Molecular Weight 54 kDa
Observed Molecular Weight 45-48 kDa
GenBank Accession NumberNM_005938
Gene Symbol FOXO4
Gene ID (NCBI) 4303
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 20ul sizes contain 0.1% BSA.

Background Information

FOXO4, also named as AFX, AFX1 and MLLT7, is a transcription factor which involved in the regulation of the ins signaling pathway. It binds to ins-response elements (IREs) and can activate transcription of IGFBP1.FOXO down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias. The antibody can recognize isoform 1 and isoform Zeta of FOXO4.


Product Specific Protocols
WB protocol for FOXO4 antibody 19121-1-APDownload protocol
IF protocol for FOXO4 antibody 19121-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols



Neurosci Lett

Expression of FOXO transcription factors in the brain following traumatic brain injury.

Authors - Xi-Lin Liu