GABARAPL2-Specific Antibody 5 Publications

Rabbit Polyclonal| Catalog number: 18724-1-AP

Featured Product KD/KO validated

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Freight/Packing

Con: 48 μg/150 μl

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Species specificity:
human, mouse, rat

Positive WB detected in:
COLO 320 cells, human brain tissue, mouse brain tissue, mouse spleen tissue, PC-3 cells

Positive IHC detected in:
human heart tissue, human brain tissue

Positive FC detected in:
HepG2 cells

Recommended dilution:
WB : 1:500-1:1000
IHC : 1:20-1:200

Product Information


Source:
Rabbit

Purification method:
Antigen affinity purification

Isotype:
IgG

Storage:
PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC. Aliquoting is unnecessary for -20oC storage.

Immunogen Information


Immunogen:
Peptide

Full name:
GABA(A) receptor-associated protein-like 2

Calculated molecular weight:
14 kDa

Observed molecular weight:
14 kDa

GenBank accession number:

Gene ID (NCBI):

Gene symbol
GABARAPL2

Synonyms
ATG8, FLC3A, GABARAPL2, GATE 16, GATE16, GEF 2, GEF2
Background

GABARAPL2 (also known as Golgi-associated ATPase enhancer of 16 kDa; GATE-16) was originally characterized as a factor essential for intra-Golgi protein transport. Later GABARAPL2 along with LC3 and GABARAP, were identified as the homologs of yeast ATG8 which is a unique ubiquitin-like protein essential for autophagy. When induced GABARAPL2 is first digested by ATG4 family enzymes to become its mature form: GABARAPL2-I, later conjugated to PE lipid as lipidated form: GABARAPL2-II. The lipidated form migrates faster than its mature form on SDS-PAGE gel. GABARAPL2 is strongly expressed in the brain. This antibody is specific to GABARAPL2. It has no cross-reaction to other GABARAP protein.


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